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. Author manuscript; available in PMC: 2009 Sep 30.
Published in final edited form as: Curr Biol. 2004 May 25;14(10):885–890. doi: 10.1016/j.cub.2004.03.059

Figure 3. Lifespan Extension by dTsc2 Overexpression Is Dependent on the Concentration of Yeast Extract in the Diet.

Figure 3

Logrank test was used to calculate the p values. The plus symbol indicates the parental strain w1118. Mean lifespan at 29°C of adult male da-Gal4/+ (closed triangles) and da-GAL4/UAS-dTSC2 (closed squares) flies were: on 0.1% yeast extract, da-Gal4/+, 33 days (n = 125) and da-GAL4/UAS-dTSC2, 30 days (n = 164); on 0.3% yeast extract, da-Gal4/+, 31 days (n = 139) and da-GAL4/UAS-dTSC2, 33 days (n = 138); on 1% yeast extract, da-Gal4/+, 30 days (n = 182) and da-GAL4/UAS-dTSC2, 34 days (n = 164); on 3% yeast extract, da-Gal4/+, 28 days (n = 181) and da-GAL4/UAS-dTSC2, 34 days (n = 154); on 9% yeast extract, da-Gal4/+, 12 days (n = 150) and da-GAL4/UAS-dTSC2, 24 days (n = 156). Mean lifespan differences between flies overexpressing dTsc2 and controls were −9% (p < 0.3), +5% (p < 0.03), +13% (p < 0.0001), +23% (p < 0.0001), and 95% (p < 0.0001) when lifespan was measured on fly food containing 0.1%, 0.3%, 1%, 3%, and 9% yeast extract, respectively.