Figure 7.

Percentage change in SWA within and between conditions. Left bars (white), During the 48 h restricted-sleep condition, AdoA₁R^−/− showed a reduced percentage increase in SWA from enforced waking (during the TM-on phase) to SWS (during the TM-off phase). Right bars (gray), The increase in SWA from waking to SWS state in the restricted-sleep condition is greater than the increase in SWA from waking to SWS in baseline condition and this is quantified as percentage change in SWA (y-axis). This additional increase during restricted sleep is significantly greater for the AdoA₁R^f/f mice compared with the AdoA₁R^−/− mice. Error bars indicate SEM.