1 |
PB |
59 |
resistant to or relapsed from various treatment including Interferon, imatinib, dasatinib, fludarabine+Ara-C bid, and intravenous homoharringtonine + imatinib |
F317L |
myeloid |
2 |
PB |
17 |
resistant to various therapies including Interferon + low dose Ara-C, imatinib, nilotinib, and dasatinib |
wt |
myeloid |
3 |
PB |
58 |
resistant to imatinib and nilotinib |
F317L |
lymphoid |
4 |
PB |
58 |
achieved short hematological remission with Idarubicin+Ara-C / imatinib but soon after had evidence of Ph+ chromosome, resistant to dasatinib and MK-0457 |
T315I |
myeloid |
5 |
BM |
60 |
achieved hematological response with imatinib and dasatinib, achieved and then lost cytogenetic response to dasatinib, was on bosutinib |
V299L |
myeloid |