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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Mol Cancer Ther. 2009 Sep 1;8(9):2509–2516. doi: 10.1158/1535-7163.MCT-09-0386

Table 2. Characteristics of Patients with CML whose CD34+ Cells were Used for Testing Triptolide Sensitivity.

patient source blast % treatment and responses at the time of sampling Bcr-Abl mutation status BC lineage
1 PB 59 resistant to or relapsed from various treatment including Interferon, imatinib, dasatinib, fludarabine+Ara-C bid, and intravenous homoharringtonine + imatinib F317L myeloid
2 PB 17 resistant to various therapies including Interferon + low dose Ara-C, imatinib, nilotinib, and dasatinib wt myeloid
3 PB 58 resistant to imatinib and nilotinib F317L lymphoid
4 PB 58 achieved short hematological remission with Idarubicin+Ara-C / imatinib but soon after had evidence of Ph+ chromosome, resistant to dasatinib and MK-0457 T315I myeloid
5 BM 60 achieved hematological response with imatinib and dasatinib, achieved and then lost cytogenetic response to dasatinib, was on bosutinib V299L myeloid