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. 2009 Aug 10;27(27):4619–4629. doi: 10.1200/JCO.2008.17.2775

Table 3.

Ketoconazole Interaction With Other Drugs

Drugs Potentiated by Ketoconazole by Degree of Effect
Drugs Contraindicated With Ketoconazole
Major Moderate Minor Synergistic
Aprepitan Amlodipine Armodafinil Amprenavir Alprazolam
Fentanyl Benzodiazepines Ciclesonide Darunavir Astemizole
Irinotecan Budesonide Etoposide Doxorubicin Cisapride
Lapatinib Coumarin-like Mifepristone Erythromycin Ergotamine
Levomethadyl Cyclosporine Modafinil Fosamprenavir
Midazolam Docetaxel Phenytoin Lopinavir
Simvastatin Methylprednisone Vinorelbine Ritonavir
Statins Donepezil
Sunitinib Erlotinib
Temsirolimus Estrogens
Felodipine
Fluticasone
Gefitinib
Imatinib
Indinavir
Isoniazid
Mefloquine
Methadone
Nifedipine
Prednisolone
Quinidine
Salmeterol
Tacrolimus
Tretinoin