Table 2.
Clinical Characteristics of Study Participants
| Clinical Characteristic | Cases (n = 246) |
Controls (n = 245) |
P | ||
|---|---|---|---|---|---|
| No. | % | No. | % | ||
| Years since cancer diagnosis | |||||
| Mean | 12.6 | 11.0 | NA | ||
| SD | 6.6 | 4.9 | |||
| Median | 10.8 | 10.3 | .052* | ||
| Years since surgery | |||||
| Mean | 12.0 | 10.7 | NA | ||
| SD | 6.9 | 5.2 | |||
| Median | 9.8 | 9.9 | .20* | ||
| SEER summary stage | .94† | ||||
| Local | 123 | 50.0 | 135 | 55.1 | NA |
| Regional | 98 | 39.8 | 104 | 42.5 | NA |
| Distant | 2 | 0.8 | 4 | 1.6 | NA |
| Unknown | 23 | 9.4 | 2 | 0.8 | < .001‡ |
| Chemotherapy | .95§ | ||||
| Preoperative | 29 | 11.8 | 12 | 4.9 | NA |
| Postoperative | 58 | 23.6 | 79 | 32.2 | NA |
| Timing unknown | 6 | 2.4 | 7 | 2.9 | NA |
| None | 137 | 55.7 | 146 | 59.6 | NA |
| Unknown | 16 | 6.5 | 1 | 0.4 | < .001‡ |
| Radiation therapy | .002§ | ||||
| Preoperative | 32 | 13.0 | 11 | 4.5 | NA |
| Postoperative | 50 | 20.3 | 44 | 18.0 | NA |
| Timing unknown | 18 | 7.3 | 17 | 6.9 | NA |
| None | 133 | 54.1 | 173 | 70.6 | NA |
| Unknown | 13 | 5.3 | 0 | 0.0 | < .001‡ |
| Type of stoma | |||||
| Colostomy | 226 | 93.4 | NA | NA | |
| Ileostomy | 10 | 4.1 | NA | NA | |
| Unknown | 10 | 4.1 | NA | NA | |
| Charlson-Deyo index, > 2 | 58 | 23.6 | 44 | 18.0 | .13 |
Abbreviations: NA, not applicable; SD, standard deviation; SEER, Surveillance, Epidemiology, and End Results.
*
Mann-Whitney test.
†
χ2 test for trend.
‡
Fisher's exact test.
§
Any treatment versus no treatment.