Table 3.
Comparison of dose–volume characteristics and plan parameters between functionally and anatomically optimised plans.
| Scenario |
V
20
|
FV
20
|
MLD |
MFLD |
V
PTV95
|
VPTV95:FV20 |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | F | A | F | A | F | A | F | A | F | A | F | |
| 1 | 25.2 | 23.8 | 14.7 | 13.4 | 13.8 | 13.8 | 9.7 | 9.8 | 92.9 | 93.1 | 6.3 | 7.0 |
| 2 | 29.8 | 28.9 | 21.1 | 20.1 | 16.1 | 16.0 | 12.4 | 12.2 | 93.2 | 93.2 | 4.4 | 4.4 |
| 3 | 24.5 | 24.0 | 11.1 | 8.1 | 14.0 | 14.0 | 9.9 | 9.2 | 91.0 | 91.0 | 8.2 | 11.2 |
| 4 | 30.4 | 29.5 | 17.3 | 16.8 | 15.8 | 15.4 | 11.0 | 10.7 | 91.1 | 91.0 | 5.3 | 5.4 |
| 5 | 24.5 | 22.4 | 14.6 | 11.9 | 13.7 | 13.3 | 9.9 | 9.4 | 90.4 | 90.3 | 6.2 | 7.6 |
| 6 | 25.6 | 24.1 | 7.2 | 3.7 | 13.7 | 13.7 | 8.2 | 7.6 | 91.8 | 91.4 | 12.8 | 24.6 |
| 7 | 20.9 | 18.2 | 10.1 | 6.6 | 10.8 | 10.6 | 7.1 | 6.7 | 90.4 | 91.4 | 8.9 | 13.8 |
| Median | 25.2 | 24.0 | 14.6 | 11.8 | 13.8 | 13.8 | 9.9 | 9.4 | 91.8 | 91.4 | 6.3 | 7.6 |
| p Value | 0.02 | 0.02 | 0.07 | 0.03 | 1.00 | 0.02 | ||||||
Data are presented for the most favourable plan generated using anatomical data (A), and with combined anatomical and functional data (F). Abbreviations: V2, percent volume of lung receiving ≥20 Gy; FV20, percent volume of functional lung receiving ≥20 Gy; MLD, mean lung dose in Gy; MFLD, mean functional lung dose in Gy; VPTV95, percent volume of planning target volume (PTV) covered by the 95% isodose; VPTV95:FV20, plan quality index consisting of the ratio of VPTV95 to FV20.