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. Author manuscript; available in PMC: 2010 Sep 2.
Published in final edited form as: J Am Chem Soc. 2009 Sep 2;131(34):12483–12493. doi: 10.1021/ja9046747

Table 2.

Examination of Possible LiCl Inhibitors.

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entry inhibitor equiv. ee (%)
1 none 2

2 TEEDA 0.2 55
3 TEEDA 0.4 76
4 TEEDA 0.8 83
5 TEEDA 1.0 83
6 TEEDA 1.2 77 low conversion
7 TEEDA 0.8 89 t-BuOMe/Tol = 1:5
8 TEEDA 0.8 92b t-BuOMe/Tol = 1:5

9 TMEDA 0.8 81
10 TMEDA 1.0 81

11 PMDET 0.1 51
12 PMDET 0.2 80
13 PMDET 0.4 71
a

Solvent = t-BuOMe/Hex = 1:3 unless noted.

b

Addition conducted at 0 °C.

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