Fig. 4.

Effects of low-dose asenapine (a) or high-dose asenapine (b) on the inhibition of PPI induced by apomorphine collapsed across prepulse intensity and for each prepulse intensity (inset). PPI prepulse inhibition, s.c. subcutaneous, Veh vehicle. *P < 0.001; **P < 0.0001 (vehicle pretreatment + apomorphine treatment vs vehicle pretreatment + vehicle treatment). ^†aP < 0.05; ^†bP < 0.01; ^†cP < 0.001; ^†dP < 0.0001 (vehicle pretreatment + apomorphine treatment vs asenapine treatment + apomorphine treatment). ^‡aP < 0.05; ^‡bP < 0.01; ^‡cP < 0.001(vehicle pretreatment + vehicle treatment vs asenapine treatment + vehicle treatment)