Table 1.
Demographics and Clinical Factors of Patient Cohort Stratified by Anatomic Region of Lymph Node Dissection (LND)
| Neck (n = 626) | Axillary (n = 762) | Inguinal (n = 960) | |||||
|---|---|---|---|---|---|---|---|
| Characteristic | P | ||||||
| No. of patients | (%) | No. of patients | (%) | No. of patients | (%) | ||
| Age | < .0001 | ||||||
| <50 years | 205 | (32.7) | 261 | (34.3) | 414 | (43.1) | |
| ≥50 years | 421 | (67.3) | 501 | (65.7) | 546 | (56.9) | |
| Sex | < .0001 | ||||||
| Male | 494 | (78.9) | 478 | (62.7) | 433 | (45.1) | |
| Female | 132 | (21.1) | 284 | (37.3) | 527 | (54.9) | |
| Race | < .0001 | ||||||
| Caucasian | 621 | (99.2) | 743 | (97.5) | 902 | (93.9) | |
| African American | 2 | (0.3) | 4 | (0.5) | 19 | (2.0) | |
| Other | 3 | (0.5) | 15 | (2.0) | 39 | (4.1) | |
| Marital status | NS | ||||||
| Married | 407 | (65.0) | 474 | (62.2) | 573 | (59.7) | |
| Unmarried | 197 | (31.5) | 266 | (34.9) | 360 | (37.5) | |
| Unknown | 22 | (3.5) | 22 | (2.9) | 27 | (2.8) | |
| Year of diagnosis | NS | ||||||
| 1988–1997 | 89 | (14.2) | 90 | (11.8) | 128 | (13.3) | |
| 1998–2002 | 283 | (45.2) | 310 | (40.7) | 424 | (44.2) | |
| 2003–2005 | 254 | (40.6) | 362 | (47.5) | 408 | (42.5) | |
| Region | NS | ||||||
| West | 372 | (59.4) | 485 | (63.6) | 588 | (61.2) | |
| North Central | 90 | (14.4) | 84 | (11.0) | 120 | (12.5) | |
| Northeast | 87 | (13.9) | 111 | (14.6) | 143 | (14.9) | |
| South | 77 | (12.3) | 82 | (10.8) | 109 | (11.4) | |
| Histology | < .0001 | ||||||
| Superficial spreading | 116 | (18.5) | 147 | (19.3) | 192 | (20.0) | |
| Nodular | 159 | (25.4) | 214 | (28.1) | 238 | (24.8) | |
| Acral lentiginous | 2 | (0.3) | 26 | (3.4) | 87 | (9.1) | |
| Other/unknown | 349 | (55.8) | 375 | (49.2) | 443 | (46.1) | |
| Thickness | NS | ||||||
| T1 (≤ 1 mm) | 137 | (21.9) | 204 | (26.8) | 233 | (24.3) | |
| T2 (1.01 – 2.0 mm) | 95 | (15.2) | 125 | (16.4) | 157 | (16.4) | |
| T3 (2.01 – 4.0 mm) | 121 | (19.3) | 143 | (18.7) | 202 | (21.0) | |
| T4 (> 4.0 mm) | 106 | (16.9) | 105 | (13.8) | 146 | (15.2) | |
| Unknown | 167 | (26.7) | 185 | (24.3) | 222 | (23.1) | |
| Clark level | .005 | ||||||
| II–III | 79 | (12.6) | 118 | (15.5) | 131 | (13.6) | |
| IV–V | 409 | (65.3) | 509 | (66.8) | 685 | (71.4) | |
| Unknown | 138 | (22.1) | 135 | (17.7) | 144 | (15.0) | |
| Primary tumor ulceration | NS | ||||||
| Yes | 99 | (15.8) | 112 | (14.7) | 168 | (17.5) | |
| No/unknown | 527 | (84.2) | 650 | (85.3) | 792 | (82.5) | |
| N stage | <.0001 | ||||||
| N1 (1 positive LN) | 327 | (52.3) | 524 | (68.8) | 496 | (51.7) | |
| N2 (2–3 positive LN) | 198 | (31.6) | 165 | (21.6) | 326 | (33.9) | |
| N3 (≥ 4 positive LN) | 101 | (16.1) | 73 | (9.6) | 138 | (14.4) | |
Abbreviation: NS, not significant; No., number, LN, lymph node