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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: J Am Stat Assoc. 2008 Mar 1;103(481):61–73. doi: 10.1198/016214507000000329

Table 10.

Estimation of overall and rater-specific sensitivity and specificity as well as prevalence for digital radiography using partial verification designs

Rater Estimator r = .10 r = .20 r = .50 r = .80




FM GRE FM GRE FM GRE FM GRE
Overall Pd .21 (.05) .22 (.07) .22 (.05) .23 (.06) .23 (.04) .24 (.05) .24 (.04) .24 (.04)
SENS .84 (.08) .80 (.14) .82 (.08) .78 (.11) .78 (.07) .76 (.07) .76 (.06) .76 (.06)
SPEC .90 (.02) .89 (.02) .90 (.02) .90 (.02) .91 (.02) .90 (.02) .91 (.01) .91 (.01)
Pd .20 (.05) .23 (.06) .21 (.05) .22 (.05) .23 (.04) .23 (.04) .24 (.04) .24 (.04)
1 SENS .81 (.13) .75 (.16) .76 (.13) .72 (.15) .71 (.11) .69 (.11) .68 (.10) .67 (.10)
SPEC .99 (.01) 1.00 (.01) .99 (.01) 1.00 (.01) .99 (.01) .99 (.01) .99 (.01) .99 (.01)
2 SENS .85 (.09) .76 (.13) .83 (.09) .76 (.12) .80 (.09) .76 (.10) .79 (.08) .77 (.09)
SPEC .86 (.04) .86 (.05) .87 (.04) .86 (.05) .87 (.04) .87 (.04) .97 (.04) .87 (.04)
3 SENS .62 (.13) .55 (.14) .57 (.14) .53 (.14) .54 (.11) .52 (.11) .52 (.11) .51 (.11)
SPEC .99 (.01) .99 (.01) .99 (.01) .99 (.01) .99 (.011 .99 (.01) .99 (.01) .99 (.01)
4 SENS .96 (.07) .90 (.14) .93 (.08) .88 (.13) .87 (.09) .85 (.10) .83 (.08) .83 (.08)
SPEC .97 (.03) .98 (.03) .97 (.03) .98 (.03) .97 (.02) .97 (.02) .97 (.02) .97 (.02)
5 SENS .95 (.07) .87 (.12) .92 (.08) .86 (.11) .88 (.08) .86 (.09) .86 (.06) .85 (.08)
SPEC .72 (.05) .72 (.06) .72 (.05) .72 (.05) .72 (.05) .72 (.05) .72 (.05) .72 (.05)
6 SENS .91 (.08) .82 (.13) .90 (.08) .83 (.11) .88 (.07) .85 (.09) .89 (.06) .87 (.07)
SPEC .86 (.04) .86 (.05) .87 (.04) .87 (.05) .88 (.04) .88 (.04) .89 (.03) .88 (.04)

NOTE: Individuals were resampled with replacement to obtain a resampled dataset of 113 patients. Verification was done completely at random with probability r. One thousand resampled datasets were obtained and means (SE) across these datasets are presented. Both the GRE and the FM models were used for estimation.