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. Author manuscript; available in PMC: 2009 Oct 2.
Published in final edited form as: J Cereb Blood Flow Metab. 2008 Aug 20;29(1):87–97. doi: 10.1038/jcbfm.2008.93

Figure 2.

Figure 2

Effects of NIM811 and CsA on motor dysfunction at 48 h (A) and 7 days (B) after severe CCI. Plotted is the mean (±s.e.m.) composite Neuroscore value for each group, including sham, noninjured animals. TBI causes significant decrease in the composite Neuroscore of vehicle-treated animals. Treatment with either 10 mg/kg of NIM811 or 20 mg/kg of CsA at 15 mins and 24 h postinjury significantly improved the motor function at both 48 h and 7 days. Statistical differences (one-way ANOVA and Student–Neuman—Keuls post hoc test): *P < 0.05 versus sham, @P < 0.05 versus vehicle, n = 12.