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. Author manuscript; available in PMC: 2009 Oct 2.
Published in final edited form as: Gynecol Oncol. 2005 Jan;96(1):32–41. doi: 10.1016/j.ygyno.2004.09.057

Fig. 1.

Fig. 1

Schematic representation of PRB and PRA with nuclear localization signals (NLS). The NLS in PR is a large region extending over the hinge region and the second zinc finger. The C-terminal region is constitutively active and the N-terminal region is active only in the presence of ligand or by deletion of the hormone binding domain (HBD). DBD = DNA binding domain; BUS = B upstream segment unique to PRB.