Table 1.

Binding constants and first-order rate constants for oxidations of styrene by cytochrome P450 Compounds I.^a

Enzyme	Temp (°C)b	Kbind (M−1)	kox (s−1)
CYP102HD	−35	1,250 ± 190	0.192 ± 0.008
	− 30	920 ± 43	0.381 ± 0.007
	−20	440 ± 120	1.28 ± 0.19
	−10	210 ± 100	4.1 ± 1.7
	22c	36	90
CYP119	−50	254 ± 16	0.098 ± 0.003
	−35	170 ± 15	0.84 ± 0.04
	−25	99 ± 9	2.64 ± 0.20
	22c	26	300

^aErrors listed are at 1σ.

^b± 0.2 °C.

^cValues for 22 °C are extrapolated from the low temperature results.