Table 1.
Proteins identified by mass spectrometry (≥ 4 out of 6 Subjects) but not detected by microarray (≥ 4 out of 6 Subjects)
| protein group | IPI IDs | gene name | max sequence coverage (%) | max unique peptides | protein name(s) |
|---|---|---|---|---|---|
| 9 | IPI00001539 | ACAA2 | 13 | 4 | 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL. |
| 37 | IPI00005158; IPI00334291 | LONP1 | 11 | 9 | LON PROTEASE HOMOLOGUE, MITOCHONDRIAL PRECURSOR; CDNA FLJ39307 FIS, CLONE OCBBF2013208, HIGHLY SIMILAR TO MITOCHONDRIALLON PROTEASE. |
| 60 | IPI00009253; IPI00445144 | NAPA | 19 | 4 | ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN; CDNA FLJ44555 FIS, CLONE UTERU3007640, HIGHLY SIMILAR TO HOMO SAPIENSN-ETHYLMALEIMIDE-SENSITIVE FACTOR ATTACHMENT PROTEIN, ALPHA. |
| 78 | IPI00011229 | CTSD | 14 | 4 | CATHEPSIN D PRECURSOR. |
| 79 | IPI00011250; IPI00647149 | UCHL3 | 24 | 4 | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L3; 17 KDA PROTEIN. |
| 93 | IPI00013723 | PIN1 | 30 | 3 | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1. |
| 97 | IPI00013894; IPI00479946 | STIP1 | 17 | 10 | STRESS-INDUCED-PHOSPHOPROTEIN 1; STIP1 PROTEIN. |
| 127 | IPI00018246; IPI00220663; IPI00220665; IPI00220667 | HK1 | 22 | 20 | ISOFORM 1 OF HEXOKINASE-1; ISOFORM 2 OF HEXOKINASE-1; ISOFORM 3 OF HEXOKINASE-1; ISOFORM 4 OF HEXOKINASE-1. |
| 129 | IPI00018398 | PSMC3 | 10 | 3 | 26S PROTEASE REGULATORY SUBUNIT 6A. |
| 132 | IPI00018740 | IDI2 | 30 | 5 | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE 2. |
| 142 | IPI00020210 | DYSF | 5 | 10 | DYSFERLIN_V1. |
| 160 | IPI00021841 | APOA1 | 42 | 12 | APOLIPOPROTEIN A-I PRECURSOR. |
| 161 | IPI00021890; IPI00747151 | HSD17B8 | 16 | 3 | ESTRADIOL 17-BETA-DEHYDROGENASE 8; 24 KDA PROTEIN. |
| 171 | IPI00022463; IPI00798430 | TF | 20 | 14 | SEROTRANSFERRIN PRECURSOR.; TRANSFERRIN VARIANT (FRAGMENT). |
| 179 | IPI00024046 | CDH13 | 8 | 4 | CADHERIN-13 PRECURSOR. |
| 182 | IPI00024664; IPI00375145 | USP5 | 15 | 9 | ISOFORM LONG OF UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5; ISOFORM SHORT OF UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5. |
| 202 | IPI00025874 | RPN1 | 9 | 4 | DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE-PROTEIN GLYCOSYLTRANSFERASE 67 KDASUBUNIT PRECURSOR. |
| 275 | IPI00100980 | EHD2 | 18 | 9 | EH DOMAIN-CONTAINING PROTEIN 2. |
| 283 | IPI00164623; IPI00783987 | C3 | 21 | 24 | 187 KDA PROTEIN.; COMPLEMENT C3 PRECURSOR (FRAGMENT). |
| 295 | IPI00176903; IPI00513773 | PTRF | 18 | 5 | ISOFORM 1 OF POLYMERASE I AND TRANSCRIPT RELEASE FACTOR; ISOFORM 2 OF POLYMERASE I AND TRANSCRIPT RELEASE FACTOR. |
| 303 | IPI00215715; IPI00745082 | CAMK2A | 13 | 4 | ISOFORM A OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II ALPHACHAIN; CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE IIA ISOFORM 2. |
| 310 | IPI00215983 | CA1 | 56 | 10 | CARBONIC ANHYDRASE 1. |
| 314 | IPI00216138 | TAGLN | 39 | 8 | TRANSGELIN. |
| 325 | IPI00217458 | GPT | 17 | 6 | ALANINE AMINOTRANSFERASE 1. |
| 326 | IPI00217466 | HIST1H1D | 21 | 5 | HISTONE H1.3. |
| 328 | IPI00217871; IPI00647328 | ALDH4A1 | 20 | 8 | DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIALPRECURSOR; ALDEHYDE DEHYDROGENASE 4 FAMILY, MEMBER A1. |
| 366 | IPI00219772 | NDUFB7 | 12 | 3 | NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7. |
| 387 | IPI00221127 | MYLK2 | 18 | 9 | MYOSIN LIGHT CHAIN KINASE 2, SKELETAL/CARDIAC MUSCLE. |
| 407 | IPI00293867; IPI00472043 | DDT | 34 | 4 | D-DOPACHROME DECARBOXYLASE; SIMILAR TO D-DOPACHROME TAUTOMERASE. |
| 409 | IPI00294073 | COQ7 | 27 | 5 | UBIQUINONE BIOSYNTHESIS PROTEIN COQ7 HOMOLOGUE. |
| 415 | IPI00295386 | CBR1 | 21 | 5 | CARBONYL REDUCTASE [NADPH] 1. |
| 435 | IPI00301028 | TRIM72* | 38 | 14 | ISOFORM 1 OF TRIPARTITE MOTIF-CONTAINING PROTEIN 72. |
| 438 | IPI00302592; IPI00333541; IPI00644576 | FLNA | 7 | 10 | FILAMIN A, ALPHA; FILAMIN-A; FILAMIN A, ALPHA. |
| 443 | IPI00303882 | M6PRBP1 | 28 | 8 | ISOFORM B OF MANNOSE-6-PHOSPHATE RECEPTOR-BINDING PROTEIN 1. |
| 452 | IPI00307755 | PRKAA2 | 8 | 4 | 5′-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2. |
| 463 | IPI00220906; IPI00333838 | ACOT1; ACOT2 | 15 | 5 | ISOFORM 1 OF ACYL-COENZYME A THIOESTERASE 2; ACYL-COENZYME A THIOESTERASE 1. |
| 470 | IPI00376005; IPI00411704 | EIF5A | 26 | 3 | ISOFORM 2 OF EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1.; ISOFORM 1 OF EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1. |
| 476 | IPI00011454; IPI00383581; IPI00441414; IPI00472068 | GANAB | 9 | 5 | ISOFORM 2 OF NEUTRAL ALPHA-GLUCOSIDASE AB PRECURSOR; ISOFORM 1 OF NEUTRAL ALPHA-GLUCOSIDASE AB PRECURSOR; ISOFORM 3 OF NEUTRAL ALPHA-GLUCOSIDASE AB PRECURSOR; 107 KDA PROTEIN. |
| 477 | IPI00384280 | PCYOX1 | 8 | 4 | PRENYLCYSTEINE OXIDASE PRECURSOR. |
| 502 | IPI00420049; IPI00739670 | C1orf170 | 14 | 5 | SIMILAR TO ZK84.1; SIMILAR TO ZK84.1. |
| 522 | IPI00470535 | CACNA2D1 | 8 | 7 | DIHYDROPYRIDINE RECEPTOR ALPHA 2 SUBUNIT |
| 541 | IPI00554737 | PPP2R1A | 24 | 10 | SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT AALPHA ISOFORM. |
| 554 | IPI00745872 | ALB | 46 | 33 | ISOFORM 1 OF SERUM ALBUMIN PRECURSOR. |
| 555 | IPI00216256; IPI00746165 | WDR1 | 20 | 6 | ISOFORM 2 OF WD REPEAT PROTEIN 1; ISOFORM 1 OF WD REPEAT PROTEIN 1. |
| 564 | IPI00792715 | ENO2 | 7 | 2 | 37 KDA PROTEIN. |
| 565 | IPI00793379 | 35 | 44 | 165 KDA PROTEIN. | |
| 593 | IPI00008964 | RAB1B | 37 | 5 | RAS-RELATED PROTEIN RAB-1B. |
| 605 | IPI00012272 | MYBPH | 14 | 4 | MYOSIN-BINDING PROTEIN H. |
| 635 | IPI00022432; IPI00646384 | TTR | 33 | 3 | TRANSTHYRETIN PRECURSOR.; 13 KDA PROTEIN. |
| 636 | IPI00022488 | HPX | 10 | 4 | HEMOPEXIN PRECURSOR. |
| 637 | IPI00022977 | CKB | 16 | 4 | CREATINE KINASE B-TYPE. |
| 639 | IPI00024107; IPI00218467; IPI00788661 | SNCA | 45 | 4 | ISOFORM 1 OF ALPHA-SYNUCLEIN.; ISOFORM 2–4 OF ALPHA-SYNUCLEIN.; 12 KDA PROTEIN. |
| 654 | IPI00030154; IPI00479722; IPI00748256 | PSME1 | 33 | 8 | PROTEASOME ACTIVATOR COMPLEX SUBUNIT 1; 29 KDA PROTEIN.; PROTEASOME ACTIVATOR SUBUNIT 1 ISOFORM 2. |
| 656 | IPI00032633 | COQ6 | 7 | 3 | UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6. |
| 665 | IPI00168620 | ADPRHL1 | 14 | 4 | ISOFORM 1 OF [PROTEIN ADP-RIBOSYLARGININE] HYDROLASE-LIKE PROTEIN 1. |
| 675 | IPI00217960; IPI00396630 | LOC730418; PRKACA | 21 | 6 | ISOFORM 2 OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT; ISOFORM 1 OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT. |
| 708 | IPI00329646 | PCBD2 | 36 | 4 | PTERIN-4 ALPHA-CARBINOLAMINE DEHYDRATASE 2. |
| 712 | IPI00394809 | APOOL | 27 | 6 | APOLIPOPROTEIN O-LIKE PRECURSOR. |
| 787 | IPI00032313 | S100A4 | 28 | 3 | PROTEIN S100-A4 |