. Author manuscript; available in PMC: 2009 Oct 2.

Published in final edited form as: J Am Chem Soc. 2008 May 2;130(21):6662–6663. doi: 10.1021/ja0777990

Table 1.

Gd(III) Ionic and Molecular Relaxivities of the New MRI Contrast Agents 4, 5, and 6 at 60 MHz, 37 °C

compounds	MW (g/mol)	Gd ionic r₁ (mM⁻¹ s⁻¹)	no. of Gd	molecular r₁ (mM⁻¹ s⁻¹)
Gd-DOTA-alkyne derivative	595.70	3.21	1	3.21
4	2030.34	5.90 ±0.15	3	17.7 ± 0.47
5	3982.57	10.97 ±0.13	6	65.8 ± 0.76
6	5480.01	12.20 ±0.54	7	85.4 ±3.74