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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Mol Cancer Res. 2009 Jun 2;7(6):907–915. doi: 10.1158/1541-7786.MCR-08-0326

FIGURE 7.

FIGURE 7

LL-37 increases the release of protumorigenic molecules from ovarian cancer cells. A. Serum-starved ovarian cancer cells were treated with 5 μg/mL of LL-37 for 48 h, then conditioned medium was analyzed by Luminex-based cytokine arrays. The amount of cytokines and growth factors in conditioned medium is represented graphically. B. Ptx-treated SK-OV-3 cells, SK-OV-3 nontarget cells, and SK-OV-3/FPRL1 KD-2 cells were treated with LL-37 as above. The levels of EGF, CXCL10, and PDGF-BB were measured in conditioned medium after 48 h. Columns, mean of three or more independent experiments; bars, SE (*, P < 0.05; **, P < 0.01; ***, P < 0.001).