Flow chart for improving the selective therapeutic effect of combination hyperthermia and liposomal therapies through the use of non-invasive imaging. This review focuses on the section inside the dashed box. Liposomal thermometry is described in this review in the section of the same name 30, 31. Drug level quantification (chemodosimetry), drug distribution patterning, and maximization of treatment are described in this review in the section Liposomes, chemodosimetry, and drug distribution patterning 10, 11,. Other (background) block elements are described throughout this text and covered in depth in other reviews 4, 8, 17.