Figure 1.
The binding site of AChBP, thought to resemble that of nAChRs. Shown are the four principal “loops” that define the binding site2. Also highlighted are TrpB (149) studied here; its backbone carbonyl (green star); and the α carbon on position 153, which has also been mutated here. Note that loop C contributes two aromatic residues; the other loops each contribute one. Image is of pdb file 1I9B10.