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| Parameter | Control (n=6) | BIM-22493 (n=6) | Statistical analysis |
|---|---|---|---|
| Serum glucose | 219 ± 16 | 177 ± 11 | < 0.05 |
| Serum insulin (pg/ml) | 1004 ± 162 | 552 ± 89 | < 0.05 |
| HOMA-IR | 13.8 ± 2.7 | 6.0 ± 1.0 | < 0.05 |
| Triglycerides (mg/dL) | 71 ± 6 | 60 ± 7 | 0.126 |
| Total Cholesterol (mg/dL) | 173 ± 10 | 133 ± 5 | < 0.01 |
| NEFA (mEq/L) | 1.57 ± 0.10 | 1.38 ± 0.10 | 0.104 |
| Leptin (pg/ml) | 6968 ± 664 | 4866 ± 231 | <0.05 |
| Resistin (pg/ml) | 1764 ± 111 | 1525 ± 297 | 0.240 |
