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. Author manuscript; available in PMC: 2010 Mar 10.
Published in final edited form as: Nature. 2009 Aug 23;461(7261):230–235. doi: 10.1038/nature08283

Figure 3. Identification of ds RNA synthesized by the hTERT-RMRP RdRP.

Figure 3

a, Northern blotting to detect complementary sequence of RMRP in cell lines. (+) indicates samples treated with RNase. b, Northern blotting to detect the RMRP sense strand. c, hTERT expression correlates with the levels of antisense RMRP detected by RNase protection assay. Vector denotes cells infected with a control vector. d, hTERT expression correlates with the levels of the sense (S) + antisense (AS) RMRP products detected by Northern blotting. The bottom panel shows U2 RNA levels.