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. 2003 Nov 15;31(22):6428–6434. doi: 10.1093/nar/gkg875

Figure 3.

Figure 3

Sensitivity of MMR-proficient cells to cytotoxicity of B[c]PhDE. Clonogenic survival of MMR-proficient (TK6 and HCT116–3-6) and MMR-deficient (MT1 and HCT116) cells following exposure to B[c]PhDE. Cells were incubated at 37°C in medium with or without (control) B[c]PhDE, as indicated, for 1 h, and then cultured in fresh medium without the chemical. The survival of both B[c]PhDE-treated or untreated cells was determined by clonogenic analysis as described in the Materials and Methods.