FIGURE 5.
A backbone overlay of cCTnC·2Ca2+·EGCg with several structures of cCTnC. In all of the images, cCTnC is depicted in schematic form and colored in gray. EGCg is shown in stick representation, and carbon atoms are colored in purple; oxygen atoms are colored in red; and hydrogen atoms are shown in white. a, cCTnC in the cCTnC·2Ca2+·EGCg complex is overlaid with cCTnC in the cCTnC·2Ca2+ complex (PDB 3CTN) shown in magenta. b, 90° rotation about the y axis. The helices are labeled in two diagrams, and EGCg is also labeled. c, cCTnC in the cCTnC·2Ca2+·EGCg complex is overlaid with cCTnC in the cCTnC·2Ca2+·EMD 57033 complex (PDB 1IH0) shown in orange. EMD 57033 is colored with carbon atoms shown in green, sulfur atoms in yellow, oxygen atoms in red, and hydrogen atoms in white. d, 90° rotation about the y axis. EMD 57033 is identified with an arrow. e, cCTnC in the cCTnC·2Ca2+·EGCg complex is overlaid with cCTnC in the cCTnC·2Ca2+·cTnI-(34–71) complex (PDB 1J1D) shown in lime green. f, 90° rotation about the y axis. cTnI-(34–71) is labeled in both representations.
