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P2X7 siRNA silencing or pharmacological inhibition increase CNTF release of CMT1A SC after FSK stimulation. A, wild type and CMT1A SC were electroporated in the absence of siRNA (UT) or in the presence of a P2X7-specific siRNA. B, wild type and CMT1A SC were exposed, or not, to 100 nm KN-62 for 24 h. CNTF release in the culture medium was determined with a rat CNTF DuoSet kit and normalized for cell protein content. *, p < 0.05; **, p < 0.01.
