Table 2.
Means of relative expression across strain
| Relative expression by strain (mean) | ||||||
|---|---|---|---|---|---|---|
| Assay | Chr (X Mb) | Set | A/J | BALB/cJ | C57/6J | DBA/2J |
| miR-15b | 3 (69 Mb) | 1 | 1.2 | 0.9 | 0.9 | 0.7 |
| miR-34a | 4 (150 Mb) | 2 | 0.7 | 0.9 | 0.5 | 0.6 |
| miR-7a | 13 (58 Mb) | 3 | 9.1 | 7.3 | 6.2 | 6.3 |
| let-7g | 9 (106 Mb) | 3 | 29.7 | 24.2 | 26.2 | 27.6 |
| miR-195 | 11 (70 Mb) | 3 | 4.7 | 6.2 | 5.4 | 5.3 |
| miR-26a | 9 (119 Mb)a | 4B | 170 | 190 | 170 | 160 |
| miR-34c | 9 (51 Mb) | 4B | 1.5 | 2.1 | 1.2 | 0.7 |
| miR-150 | 7 (52 Mb) | 4B | 10.5 | 11.8 | 10.2 | 8.9 |
| miR-139 | 7 (109Mb) | 5 | 4.4 | 4.7 | 3.4 | 3.3 |
| miR-301a | 11 (87 Mb) | 5 | 3.0 | 3.1 | 3.1 | 2.1 |
| miR-378 | 18 (62 Mb) | 5 | 0.6 | 0.9 | 0.4 | 0.4 |
| miR-425 | 9 (108 Mb) | 5 | 0.2 | 0.2 | 0.2 | 0.3 |
| miR-9 | 3 (88 Mb)a | 7A | 160 | 160 | 160 | 150 |
| miR-30e | 4 (120 Mb) | 7A | 4.6 | 5.4 | 4.5 | 4.5 |
| miR-31 | 4 (89 Mb) | 7A | 0.8 | 0.8 | 0.8 | 0.6 |
| miR-187 | 18 (25 Mb) | 7A | 3.4 | 3.2 | 2.4 | 2.7 |
| miR-203 | 12 (113 Mb) | 7B | 0.5 | 0.1 | 0.1 | 0.1 |
| miR-451 | 11 (78 Mb) | 7B | 2.3 | 4.4 | 1.1 | 0.9 |
| miR-212 | 11 (75 Mb) | 8 | 3.1 | 3.2 | 2.7 | 1.9 |
| miR-323 | 12 (111 Mb) | 8 | 0.8 | 1.0 | 0.7 | 0.6 |
Mean relative expression across strain for the 20 miRNAs assayed in individual animals (n = 8 for all strains). Expression was normalised to the geometric mean of RNU6B, RNU19, and miR-16
aThere is more than one chromosomal location for the given miRNA: miR-26a at 9 (119 Mb) and 10 (126 Mb) and miR-9 at 3 (88 Mb), 7 (87 Mb), and 13 (84 Mb)