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. 2009 Jan 1;24(1):37–48. doi: 10.1007/s00467-008-0826-x

Table 1.

Comparison of the advantages and disadvantages of continuous renal replacement therapies (CRRT) and peritoneal dialysis (PD) and intermittent hemodialysis (IHD). IPD intermittent peritoneal dialysis, VP ventriculoperitoneal, ICU intensive care unit

Variable CRRT PD IHD
Continuous therapy Yes Yes No
Hemodynamic stability Yes Yes No
Fluid balance achieved Yes, pump controlled Yes/no, variable Yes, intermittent
Easy to perform No Yes No
Metabolic control Yes Yes Yes, intermittent
Optimal nutrition Yes No No
Continuous toxin removal Yes No/yes, depends on the nature of the toxin—larger molecules not well cleared No
Anticoagulation Yes, requires continuous anticoagulation No, anticoagulation not required Yes/no, intermittent anticoagulation
Rapid poison removal Yes/no, depending on patient size and dose No Yes
Stable intracranial pressure Yes Yes/no, less predictable than CRRT Yes/no, less predictable than CRRT
ICU nursing support Yes, high level of support Yes/no, moderate level of support (if frequent, manual cycling can be labor intensive) No, low level of support
Dialysis nursing support Yes/no, institution dependent Yes/no, institution dependent Yes
Patient mobility No Yes, if IPD used No
Cost High Low/moderate. Increases with increased dialysis fluid used High/moderate
Vascular access required Yes No Yes
Recent abdominal surgerya Yes No Yes
VP shunt Yes Yes/no, relative contraindication Yes
Prune belly syndrome Yes Yes/no, relative contraindication Yes
Ultrafiltration control Yes Yes/no, variable Yes, intermittent
PD catheter leakage No Yes No
Infection potential Yes Yes Yes
Use in AKI-associated inborn errors of metabolism Yes No Yes
Use in AKI-associated ingestions Yes No Yes

aOmphalocele, gastroschisis, frequent or extensive abdominal surgery