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Effect of VHH2 glycosylation on FMDV neutralization
| VHH(2) | Endoglycosidase H treatment | FMDV neutralization (mg/ml) |
|---|---|---|
| M180shVI-12 | − | 0.008 |
| M180shVI-12 | + | 1 |
| M200shVI-12 | − | 0.016 |
| M200shVI-12 | + | 1 |
| M180 | − | 0.22 |
| M200 | − | 0.059 |
| VI-12 | − | >10a |
| VI-12 | + | >1 |
+ endoglycosidase H treatment, − mock incubation
aNo neutralization at the highest VHH concentration used
