Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The N-terminal interaction of Syntaxin1a with Munc18-1 measured by ITC. Raw data (top panel) and integrated normalized ITC data (bottom panel) for binding of Sx1a-(2–243) to Munc18-1 WT (closed squares) and Munc18-1-F115E/E132A (closed triangles). Experiments were performed by injecting 3.1-μl aliquots of 25 μm Sx1a-(2–243) into 2.5 μm Munc18-1 proteins at 298 K.
