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Pathways of fatty acid and triglyceride syntheses from acetyl-CoA. SREBP-1 is a key regulator of lipogenic gene expression and promotes cellular TG accumulation. ACC, acetyl-CoA carboxylase; FAS, fatty acid synthase; ELOVL6, elongation of very long chain fatty acid-like 6; SCD, sterol-CoA desaturase; GPAT, glycerol-3-phosphate acyltransferase; LPIN1, lipin 1; DGAT, diacylglycerol acyltransferase.
