Fig. 7.

Effects of RSV on ROS and nitric oxide (NO) production in the lungs of SD and Ren2 rats. A: lucigenin was used to measure superoxide (O₂⁻) from fresh lung samples. B: NADPH oxidase-specific assays were also preformed (n ≥ 7). C: the sum of stable NO metabolites [nitrate and nitrite (NO_x)] was measured in lung homogenates via the Griess reaction (n ≥ 5). Significant differences were determined via ANOVA with a Tukey-Kramer post hoc test. *P < 0.05, SDC vs. R2C; ^ΩP < 0.05, SDR vs. R2C; ‡P < 0.05, R2C vs. R2R.