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Eupnea and gasping in a wild-type mouse after blockade of α1-adrenergic receptors with WB-4101. C, integrated records of phrenic discharge; W, recordings obtained 10 min after addition of 1.0 μM WB-4101 to perfusate. Incrementing pattern of phrenic discharge continued. During the period designated by the solid horizontal bar, perfusion was terminated and gasping (G) was induced. Note decrementing discharge pattern of gasping.
