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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Prostaglandins Other Lipid Mediat. 2009 Aug 12;89(3-4):140–146. doi: 10.1016/j.prostaglandins.2009.07.006

Table 1.

Summary of validated engineered tumor xenograft models

Xenograft Type or
Model
Cancer Type Cell lines sECM Used
Orthotopic Breast cancer MCF7,
MDA-MB-231,
MDA-MB-468
Extracel
Colorectal cancer HCT-116,
CaCo-2
Extracel
Pancreatic cancer MiaPaCa-2 Extracel
Ovarian cancer SK-OV-3,
OVCAR-3
Extracel
Subcutaneous NSCLC lung cancer A-549 Extracel-HP
Angiogenesis Plug Extracel-HP,
Heprasil