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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Curr Opin Pharmacol. 2009 Jan 21;9(1):65–73. doi: 10.1016/j.coph.2008.12.014

Figure 2.

Figure 2

Expansion of mu opioid hotspot in nucleus accumbens with delineation of ‘liking’ versus ‘wanting’ zones. Green: the entire medial shell mediates opioid-stimulated increases in ‘wanting’ for food reward. Orange-red: circumscribed cubic-millimeter sized hedonic hotspot generates increases in ‘liking’ after the same opioid stimulation. Blue: a small hedonic ‘coldspot’ suppresses ‘liking’ reactions to sucrose, whereas a larger purple zone suppresses ‘disliking’ reactions to quinine. Reprinted with permission from [27], based on data from [14••].