Table 6.
Central Nervous System Locations and Number of Cases Stained
IC2 | 2B4 | ||||
---|---|---|---|---|---|
Location | HD cases | Normal controls |
FTD-Uh cases |
HD cases | Normal controls |
Neocortex | 15 | 7 | 2 | 4 | 5 |
Striatum | 9 | 4 | 2 | 4 | 2 |
Hippocampus | 13 | 7 | 2 | 3 | 4 |
Lateral geniculate body | 7 | 4 | 1 | 1 | 3 |
Thalamus | 6 | 7 | 2 | 5 | 4 |
Cerebellum | 10 | 8 | 2 | 4 | 5 |
Pituitary gland | 2 | - | 1 | - | - |
Midbrain | 7 | 9 | 12 | 5 | 5 |
Pons | 10 | 9 | 12 | 5 | 5 |
Medulla | 10 | 8 | 2 | 5 | 5 |
Spinal cord | 4 | 1 | 2 | - | - |
HD, Huntington disease; 1C2, polyglutamine antibody; 2B4, N-terminal huntingtin antibody.