Table 3.

FVC responses to infusion of PGI₂ and SNP with and without co-infusion of L-NMMA

FVC (a.u.)
Drug	Young	Older	Co-infusion
PGI (ng•dl−1 FAV•min−1)			Normal Saline
Baseline	2.11 ± 0.30	2.33 ± 0.27
2.5	4.64 ± 0.86	3.42 ± 0.38
5.0	7.22 ± 1.17	5.88 ± 0.67
10.0	9.34 ± 1.35	7.17 ± 0.80
SNP (mcg•dl−1 FAV•min−1)
Baseline	3.04 ± 0.45	3.11 ± 0.38
0.25	7.56 ± 1.10	5.77 ± 0.76
0.50	11.29 ± 1.00	10.41 ± 0.99
1.0	14.85 ± 1.14	13.47 ± 1.21
PGI (ng•dl−1 FAV•min−1)			L-NMMA
Baseline	1.86 ± 0.18	1.83 ± 0.18
2.5	2.68 ± 0.30	2.44 ± 0.23
5.0	4.50 ± 0.53	4.53 ± 0.71
10.0	6.27 ± 0.61	5.99 ± 0.93
SNP (mcg•dl−1 FAV•min−1)
Baseline	2.01 ± 0.18	1.81 ± 0.21
0.25	5.80 ± 0.92	5.21 ± 0.58
0.50	9.10 ± 0.90	9.33 ± 0.98
1.0	11.06 ± 1.15	12.89 ± 1.33

Values are mean ± SEM. FVC=forearm vascular conductance, SNP=sodium nitroprusside, PGI=epoprostenol.