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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: Structure. 2009 Apr 15;17(4):489–498. doi: 10.1016/j.str.2009.02.010

Figure 2. Hypothetical Ligand Binding Energy Landscape.

Figure 2

Ligand binding energy landscapes (top) can be rough, with multiple minima. These multiple minima can correspond to multiple distinct ligand binding conformations in the receptor (bottom).