Figure 2.

5-HT does not significantly alter ventral root output power. A, Summed normalized absolute ventral root activity is plotted against time during the MLR-evoked fictive locomotion bout. Activity was measured in three sequential locomotor bouts activated at 5 min intervals from five preparations (SEM shown in gray). B, The effect of 5-HT (0.6 μm) total output power remained unchanged at 107 ± 20% of control. C, The effect of 5-HT (1 μm). Output power remained at 75 ± 14% of control. Data were normalized to the peak output power at the termination of the bout recorded under control conditions.