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. 2009 Sep 16;65(Pt 10):1118–1125. doi: 10.1107/S0907444909031011

Figure 1.

Figure 1

Three-dimensional structure of human TLC with bound 1,4-butanediol crystallized in space group P21. (a) Ribbon diagram of the four TLC monomers in the asymmetric unit (chain A, magenta; chain B, blue; chain C, green; chain D, orange). The four ligand molecules are displayed in sphere style in grey and the unit-cell boundary is indicated. (b) Stereo representation of the four superimposed TLC monomers AD (same colours as in a). Molecules were superimposed using the Cα positions of the 58 conserved β-barrel residues (Breustedt et al., 2005). The ligand 1,4-butanediol and the disulfide bond joining Cys61 and Cys153 are depicted in stick representation.