Table 4.
Changes in Composition of Infiltrating Cells in WT and GKO Mice
Week 2 |
Week 3 |
Week 4 |
Week 5 |
|||||
---|---|---|---|---|---|---|---|---|
WT (n = 8) | GKO (n = 8) | WT (n = 24) | GKO (n = 23) | WT (n = 5) | GKO (n = 5) | WT (n = 6) | GKO (n = 6) | |
Mo | 44.5 ± 5.0 | 22.7 ± 4.5 | 38.0 ± 9.9 | 21.0 ± 5.8 | 38.0 ± 7.1 | 35.5 ± 5.2 | 40.0 ± 1.4 | 54.0 ± 11.1 |
Ly | 35.0 ± 1.4 | 12.7 ± 3.1 | 41.5 ± 7.8 | 19.3 ± 5.7 | 50.5 ± 10.6 | 35.0 ± 6.5 | 46.5 ± 3.5 | 33.0 ± 8.2 |
Neut | 19.0 ± 2.8 | 54.0 ± 4.0 | 13.0 ± 7.1 | 47.7 ± 7.5 | 10.0 ± 2.8 | 24.0 ± 5.1 | 9.5 ± 0.7 | 10.0 ± 1.4 |
Eo | 2.5 ± 0.7 | 10.7 ± 3.6 | 2.0 ± 0.6 | 13.0 ± 3.8 | 3.0 ± 1.9 | 5.6 ± 2.6 | 2.0 ± 1.2 | 3.0 ± 2.2 |
Composition of infiltrating cells in uveitic eyes as a function of time after immunization is expressed as a percentage of each cell type out of total. Mo, mononcyte/macrophages; Ly, lymphocytes; Neut, neutrophils; Eo, eosinophils.