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Foxp3+ G113 Treg cell generation is saturable. Graph shows the absolute number of Foxp3+CD4SP cells from TCR transgenic mice and from irradiation and neonatal BM chimeras (Fig. 2c–d). Numbers were derived from the total number of thymocytes multiplied by the frequency of Foxp3+ G113 CD4SP T cells. Also shown is the total number of TCR transgenic CD4SP thymocytes in each mouse. Each symbol represents data from an individual mouse from 7 independent experiments.
