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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Biochim Biophys Acta. 2009 Aug 4;1790(10):1149–1160. doi: 10.1016/j.bbagen.2009.07.026

Table 2.

Toxicity of lipoic acid (LA) in animals

Model LD50 (acute oral) Ref.
Dog 400-500 mg/kg [32]
Mouse 500 mg/kg [33]
Cat 30 mg/kg [34]
Rat >2000 mg/kg [35]