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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Cancer Res. 2009 Sep 22;69(19):7569–7576. doi: 10.1158/0008-5472.CAN-09-0529

Figure 3. miR-34a inhibits brain tumor cell proliferation, cell cycle progression, cell survival and cell invasion.

Figure 3

Glioma and medulloblastoma cells were transfected with pre-miR-34a or pre-miR-con and subsequently assessed for cell proliferation by cell counting (A), for cell cycle by propidium iodide flow cytometry (B), for apoptosis by Annexin V flow cytometry and cleaved PARP immunoblotting (C) and for invasion by a transwell invasion assay (D). The results show that miR-34a strongly inhibits cell proliferation (A), induces cell cycle arrest (B), induces apoptosis (C) and inhibits transwell cell invasion (D). * = p<0.05.