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. 2009 Jun 22;587(Pt 16):4105–4119. doi: 10.1113/jphysiol.2009.175554

Table 2.

Running distance, glycaemia and morphometric values in ZDF rats

Lean Sedentary ZDF Trained ZDF
Body weight (g) 303 ± 6 382 ± 14*** 381 ± 6***
Plantaris (mg (g body weight)−1) 0.95 ± 0.03 0.58 ± 0.03*** 0.65 ± 0.03***
EWAT (mg (g body weight)−1) 3.9 ± 0.8 9.7 ± 0.4*** 9.0 ± 0.4***
Glycaemia (mg dl−1) 133 ± 3 296 ± 42*** 149 ± 19***
Mean running distance after 42 days (km) n/a n/a 4.7 ± 0.4***

Zucker Diabetic Fatty rats (ZDF) presented a higher mean body weight than Lean animals (**P≤ 0.005). Plantaris muscle was atrophied in sedentary (n= 8) and trained (n= 8) ZDF rats when compared to Lean (n= 9) animals (***P≤ 0.001). Epididymal white adipose tissue (EWAT) was significantly increased in sedentary and trained ZDF rats when compared to Lean animals (***P≤ 0.001). Glycaemia (mg dl−1) was significantly increased in sedentary ZDF rats when compared to Lean animals and trained ZDF (*P≤ 0.05). Exercise training prevented any significant increase in glycaemia in trained ZDF rats when compared to Lean animals. n/a: non applicable. Data are means ±s.e.m.