Table 1.
Oocyte injection |
Gap junction coupling |
||
---|---|---|---|
Cell 1 | Cell 2 | Mean conductance† (μS) | n |
Wild type Cx50 | Wild type Cx50 | 15.77 (3.81) | 10 |
Cx50D47N | Cx50D47N | 0.073 (0.010)* | 10 |
Wild type Cx50:Cx50D47N (1:1) | Wild type Cx50:Cx50D47N (1:1) | 21.70 (4.00) | 10 |
No connexin cRNA | No connexin cRNA | 0.073 (0.011)* | 5 |
p<0.01 as compared to wild type Cx50 by Student’s t-test
Values represent mean (SEM); n, number of cell pairs.
To facilitate comparison of the homotypic and heteromeric pair data, the amount of wild type Cx50 cRNA injected into each cell was held constant.