Skip to main content
. Author manuscript; available in PMC: 2009 Oct 4.
Published in final edited form as: Biochem Biophys Res Commun. 2009 Jul 18;387(4):646–650. doi: 10.1016/j.bbrc.2009.07.080

Fig. 2.

Fig. 2

Concentration-dependent effect of PARP inhibitors (A) and MMP inhibitors (B) on MMP-2 activity using the OmniMMP® fluorogenic substrate kinetic assay. PARP and MMP inhibitors were incubated with 0.2 nM 64 kDa MMP-2 and 15 µM OmniMMP fluorogenic substrate at 37 °C in 50 mM Tris buffer, pH 7.6, containing 10 mM CaCl2 and 10 µM ZnSO4. Data represent means ± SD of three to five replicate determinations and were fitted to sigmoidal (variable slope) curves.

HHS Vulnerability Disclosure