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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Am J Transplant. 2009 Jun 16;9(8):1773–1783. doi: 10.1111/j.1600-6143.2009.02706.x

Figure 1. Fibrosis is increased in cardiac allografts undergoing CR.

Figure 1

(A) Representative Masson’s trichrome stains, in which fibrotic tissue stains blue, of heterotopic cardiac grafts at day 30 post transplant (200x magnification). Cardiac allografts from recipients transiently depleted of CD4+ cells (Anti-CD4) or allograft recipients receiving anti-CD40L mAb therapy (Anti-CD40L) are shown along with syngeneic control grafts. (B) Morphometric analysis of trichrome staining at day 30 and 50 post transplant in groups from (A). Bars represent the combined mean + S.E.M. of fibrotic (blue) area of 10–12 frames of view per heart taken from no fewer than 6 different cardiac grafts per group.