Table 1.

Macrophage sterol levels from Ldlr^−/− mice transplanted with Abcg1^+/+ or Abcg1^−/− BM.

	Cholesterol ug/mg protein	Desmosterol ng/mg protein	Lanosterol ng/mg protein	7-ketocholesteol ng/mg protein
Abcg1+/+Ldlr−/−	82±5	563±41	765±56	156±27
Abcg1−/−Ldlr−/−	135±18*	751±38*	843±76	323±60*

Thioglycollate-elicited macrophages were obtained from 4–5 recipient mice fed a Western diet for 12 weeks and briefly cultured (1h) before sterol composition analysis by gas chromatography. Value are means ± SEM.

^*P < 0.05, significant difference vs. control mice.