Figure 2.

Increased IREB2 Protein and mRNA Expression in Human COPD Lung Tissues

Human lung-tissue homogenates from control (n = 18) and COPD (n = 22) subjects were analyzed for IREB2 protein expression by immunoblot analysis. Total IREB2 protein expression was normalized to β-actin, and the quantified results are depicted by graph. Data represent mean ± SD (n = 18 normal and n = 22 COPD patients), p < 0.01, comparing COPD lung tissue with normal lung. mRNA expression was extracted from the same lung tissues and quantified with RT-PCR (n = 11 normal and n = 20 COPD patients), p < 0.05, comparing COPD lung tissue with normal lung.