Figure 5.
Linkage Disequilibrium Map for All IREB2 SNPs Genotyped in NETT-NAS Plus Two CHRNA3 Region SNPs Previously Associated with Lung Cancer and COPD
LD map of the 12 SNPs genotyped in IREB2 in NETT-NAS demonstrate high LD across the gene. Additionally, there is high LD in the NETT-NAS cohort between the IREB2 SNPs and two SNPs in the CHRNA3 region (rs8034191, rs1051730; association data published by Pillai et al.12) Red corresponds to r2 ≥ 0.8. Values for D′ are included in the text of boxes.