Table 1.
Organism | Accession Number | GenBank cDNA (%)a | Gene Model (%)b | Confirmation by Sequencing (%)c |
Pairwise Amino Acid Sequence Identity (%)d |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Hs | Mm | Ss | Md | Gg | Xl | Dr | Bf | |||||
Homo sapiens | AAB65827.1 | 100.0 | 0.0 | 0.0 | ||||||||
Mus musculus | NP_031525.2 | 100.0 | 0.0 | 0.0 | 84.1 | |||||||
Sus scrofa | AAT01608.1 | 100.0 | 0.0 | 0.0 | 88.4 | 82.6 | ||||||
Monodelphis domestica | ACG68567.1, ACG68568.1 | 0.0 | 88.7e | 11.3 | 80.7 | 76.2 | 78.9 | |||||
Gallus gallus | XP_417160.2 | 0.0 | 99.7 + 0.3f | 0.0 | 69.5 | 66.7 | 68.5 | 70.5 | ||||
Xenopus laevis | AAT72929.1 | 100.0 | 0.0 | 64.5 | 62.7 | 63.6 | 65.9 | 64.6 | ||||
Danio rerio | BAD91491.1 ACJ03990.1 | 89.4 | 0.3f | 10.6 | 54.2 | 53.2 | 53.4 | 53.9 | 53.4 | 54.3 | ||
Branchiostoma floridae | ACG68443.1 | 0.0 | 0.0 | 100.0 | 36.9 | 36.3 | 36.6 | 36.5 | 37.2 | 37.7 | 36.6 | |
Strongylocentrotus purpuratus | ABY60856.1 | 0.0 | 0.0 | 100.0 | 34.8 | 34.6 | 34.7 | 35.0 | 35.9 | 35.3 | 35.2 | 38.1 |
This is the percentage of the ATM amino acid sequence used in our alignment that was obtained directly from a GenBank cDNA entry.
This is the percentage of the ATM amino acid sequence used in our alignment that was obtained by gene prediction.
This is the percentage of the ATM amino acid sequence used in our alignment that we confirmed by RT-PCR and sequencing from model-organism cDNA.
The two-letter species-name abbreviations are as follows: Hs, Homo sapiens; Mm, Mus musculus; Ss, Sus scrofa; Md, Monodelphis domestica; Gg, Gallus gallus; Xl, Xenopus laevis; Dr, Danio rerio; Bf, Branchiostoma floridae. Note that the cross-comparison does not require a column for Strongylocentrotus purpuratus.
Gene model built at IARC, but similar to Ensemble prediction ENSMODP00000018290.
Corrections to apparent anomalies in a gene-model prediction obtained from GenBank, made by reference to the genomic sequence.