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. Author manuscript; available in PMC: 2010 Apr 29.
Published in final edited form as: J Am Chem Soc. 2009 Apr 29;131(16):5792–5799. doi: 10.1021/ja809554x

Scheme 8. Assembly of the β-FSH subunit with N-linked chitobiose.

Scheme 8

aReagents and Conditions: (a) PhSH, Gnd·HCl, Na2HPO4, TCEPHCl (pH = 7.2); (b) NH2OMeHCl (pH = 4.6); 85% conversion, 15% yield; (c) PhSH, Gnd·HCl, Na2HPO4, TCEP·HCl (pH = 7.2), 64% yield.